Individualized treatment of lung cancer

The beginning of the year, a 55-year-old male patient with chest pain due to血痰, CT examination revealed left lower lung shadow was diagnosed as lung cancer in a hospital in the lower left pneumonectomy and mediastinal lymph node dissection and postoperative pathologic diagnosis was no lymph node metastasis in early lung adenocarcinoma. Unfortunately, this should be the extremely lucky, because the early effects of surgical treatment of lung cancer has been quite good. However, whether postoperative adjuvant therapy should be carried out to produce a heated debate. Party's view is: Although patients with early lung cancer, but the pathological type is adenocarcinoma, there are easy to transfer the tendency for insurance purposes, should be held in post-operative chemotherapy and radiotherapy to prevent recurrence and metastasis. The other view is that: Since the early days, so do not overdo plus chemotherapy and radiotherapy, not to mention the two treatments are not 100 percent effective. Two points of view refused to give joy to win, but also suffered the patients, how to choose?

Medical activities is uncertain and full of controversy and, for the best cancer treatment, almost no unanimous view, more often is the public that the public and reasonable, rational po po said.

First take a look at this case the need for postoperative radiotherapy. The 20th century, 90 years ago, many doctors for insurance purposes, often to allow lung cancer patients - whether early or late relative ---- accepted after mediastinal radiotherapy, and its purpose is to reduce local recurrence and metastasis to extend the life of patients The survival time. Unfortunately, this goal can not achieve. Through an integrated high-quality clinical research findings, we were astonished to find, for early lung cancer, using the old methods of postoperative radiotherapy, not only fail to improve survival rates, but increased mortality. The cause of death was mainly caused by radiation therapy-induced complications. Therefore, in lung cancer has been made in academic circles for such a consensus for early lung cancer, there is no need to give the old methods of postoperative radiotherapy. Of course, the premise is that these early stage lung cancer, including the same side of the mediastinal lymph nodes must be removed clean.

Well, then chemotherapy?

The so-called chemotherapy, is the adoption of several anti-cancer drugs combined into a certain program for cancer patients. As a result of intravenous drug delivery is, therefore, the drug's role is systemic, a feature that allows doctors often consider the use of chemotherapy to eliminate or prevent the transfer of specific cancer cells. However, until now, a large number of clinical research tells us that post-operative chemotherapy for early lung cancer patients would have minimal benefits, we look forward to the chemotherapy drugs significantly reduce or even eliminate the cancer cells the effect of transfer did not occur. But the chemotherapy drugs to patients has brought about obvious side effects: hair loss, vicious vomiting, leukopenia and so on. Therefore, we must in the early post-operative chemotherapy in lung cancer to choose between the pros and cons. On the current evidence available, under normal circumstances do not advocate for such patients postoperative chemotherapy.

But things is not absolute. Since the early lung cancer, in general, there was a slight benefit of postoperative chemotherapy, then the possibility of a slight overall advantage of these transformed into the absolute benefits of a particular patient? If so, how to choose the patients? How reasonable the application of anti-cancer drugs? Here, it gives us of early lung cancer patients should also be divided into two serious proposition.

In 2001, we launched a research project, that is the nature of lung cancer through research, of lung cancer by detecting changes in a number of tags to see if it early screening of lung cancer metastasis and recurrence in easy, but it is also sensitive to chemotherapeutic drugs in particular type, we call the early lung cancer in high-risk type, this type of lung cancer patients given postoperative chemotherapy, it may be targeted rather than feeling the way across the river. Day-ping to the benefit of chemotherapy in the direction of tilt, we should not hesitate to adjuvant chemotherapy patients. When we can not identify early lung cancer in high-risk type, the early post-operative chemotherapy in lung cancer patients are naturally cautious.

The tremendous progress of medical science, allow us to early lung cancer after treatment with some of the new attempt. A step forward in this regard, just the most important new drugs in foreign markets, "the Iraqi force Sand" (Iressa). Mechanism of this drug is completely different from previous chemotherapy, it will not bring to patients, such as hair loss and bone marrow transplant side effects, because it is the role of signal transduction in cells of a certain point, it is called targeted therapy. In Japan and Europe and the United States study, the Iraqi forces were on the sand refractory lung cancer can be achieved satisfactory results. Application of the former period of time, our experience also shows that the Iraqi forces sand on a small tumor burden of patients particularly effective. Therefore, in foreign countries have begun to force the Iraqi sand as postoperative adjuvant treatment of early lung cancer drugs, clinical research, believe that in the near future, we will be able to find early lung cancer one of the most appropriate model of comprehensive treatment.

The beginning of this article that patients who have not received postoperative chemotherapy or radiotherapy. Almost one year since, the patient did not show any tumor recurrence or metastasis of the signs, which initially proved correct treatment measures. Of course, the final conclusion, to be observed in recent years.

In response to the title of this article, lung cancer treatment, is not an easy task, which requires a doctor's knowledge, wisdom, courage, technology, ethics and conscience, but also of lung cancer patients and their families and with the knowledge of doctors with . What is the treatment of lung cancer better able to speak a few words is not clear, but its basic elements, that is, according to phases and physical state of the first to develop the basic principle of treatment, and then in this framework can be the basis of all patients Comprehensive after specific information to determine the details of the design of treatment, which is the highest state of lung cancer ---- individual treatment.