Tuesday, January 13, 2009

Difficulties and Countermeasures of lung cancer

Lung cancer is the most common malignant tumor of mankind is one of intractable diseases, easy to relapse and easy transfer. Although a small number of early patients were positive long-term survival after treatment available, but most patients with a variety of reasons lost the timing of early aggressive treatment. How can this part of patients receive appropriate medical treatment, so that their lives can be extended, is Chinese and Western medicine treatment of problems. Surgery, radiotherapy and chemotherapy, although for the effective treatment, but how to make the effect of better and more durable; how to reduce those in the medical treatment in these areas there are great advantages and research value.

One of the difficulties: early detection, early diagnosis of lung cancer was the key to cure

1, early detection
(1) attention to precancerous lesions of the prevention and treatment, attention to a number of carcinogenic, cancer-promoting factor in prevention. To suffer from various forms of chronic pneumonia, tuberculosis patients should pay attention to.
(2) of lung cancer screenings, as soon as possible to check and found that small, confined tumor without metastasis.
(3) to educate the masses with precancerous lesions of the lung cancer clinical manifestations of lung cancer has great importance for timely treatment.
(4) to improve the grassroots and the general hospital of lung cancer diagnosis level, there is awareness of the referral system and to reduce misdiagnosis.

2, early diagnosis methods
(1) of suspicious objects repeatedly, repeatedly falling sputum cytology.
(2) of suspicious objects, such as tumor markers inspection. Such as: CEA, electrophoresis of serum-induced factors, serum sialic acid, neural enolase, mucin 1 antigen and neural cell adhesion molecules, such as.
(3) X-ray and CT, MRI, such as inspection, the early diagnosis of lung cancer will have a very important value.
(4) bronchofibroscope cytology and organization of central lung cancer meaningful.
(5) attention to the emergence of extra-pulmonary symptoms, such as: clubbed fingers, anemia or blood cells increased, hypertrophic osteoarthropathy and recent performance of endocrine disorders.
(6) monoclonal antibody diagnosis of lung cancer in early stage and is conducive to the positioning of lung cancer diagnosis.
(7) conditions to allow the hospital to deal with suspicious objects cancer and tumor-related genetic tests. And lung cancer-related genes: c-eph, L-myc (small cell lung cancer), P21 protein.

Although more than a number of examination methods for early diagnosis of lung cancer have a certain significance, but with little specificity, attention should be given comprehensive application.

Difficulties in two: the early detection of recurrence and re-treatment

Early lung cancer patients should be regularly reviewed, paying attention to the original lesions, lungs, brain, bone, liver, kidney, adrenal gland and lymph node recurrence or metastasis, etc. there. After one year should be at least 3 months time, such as X-ray, high-resolution CT, sputum cytology examination and tumor markers of lung cancer screening.

Recurrence should be removed as soon as possible to accept the second, if the disease widespread or transfer, other methods of treatment should be selected. Regardless of which method to choose treatment, should have the participation of Chinese medicine, especially those who can not tolerate surgery or radiotherapy and chemotherapy patients should be based on traditional Chinese medicine-based treatment. Practice has proved that Chinese medicine has to participate in a comprehensive anti-cancer treatment, more effective than to accept a single surgery or radiotherapy and chemotherapy in cancer patients, and the toxicity of light, a good long-term effect.

Can not accept the surgery or radiotherapy and chemotherapy patients relapse, Chinese medicine treatment is the best option. In the disease based on the combination of differentiation, select those who are anti-cancer effect of the application of traditional Chinese medicine differentiation available good effect.

The third difficulty: the side effects of traditional Chinese and western medicine treatment of lung cancer directly affects the efficacy of

Western medicine for lung cancer certainly has some effect, but the radiotherapy and chemotherapy damage caused by the body is a serious problem, he often can not tolerate the patients give up treatment, a direct impact on treatment effect - those who had received surgery or patients boil radiochemical if the transfer or relapse, then the already insufficient blood, organs function of weakness, and then given drugs such as radiation or chemical treatment, Chinese medicine practitioners believe that this is the evil of drug fever, righteousness will undoubtedly hurt the patient more difficult to tolerate, at the same time blood and organs of the body recovery and to strengthen its anti-metastasis and recurrence of the capacity of disadvantaged. To solve these problems, Chinese medicine is superior.
1, the use of Chinese medicine Fuzheng mainly to promote the postoperative, radiotherapy and chemotherapy after the restoration of the body, such as: Chinese medicine Jianpi Bushen law, Jianpi Liqi law, Yangyin Qingre law, Yiqi Yangyin law can also be supplemented by Qi and Blood of law.
2, uphold the use of Chinese medicine to alleviate and treatment of radiotherapy and chemotherapy toxicity. Treatment commonly used are: Yangyin Qingdu heat, Jianpi Bufei, Yiqi Yangyin, Bushen myeloid radiation, such as filling method.
3, the use of Chinese medicine for radiotherapy and chemotherapy sensitizer to enhance the efficacy of extended survival.
4, use of anti-cancer effect of Chinese medicine and radiochemical boil common application, since synergistic anticancer effects.

The fourth difficulty: how to solve the chemotherapy multi-drug resistance problems

Multidrug resistance in tumor chemotherapy efficacy of the main obstacles -, once the tumor cells to chemotherapeutic drug resistance, the structure and function of other different chemotherapeutic agents were also resistant. Multidrug resistance to solve the fundamental problem is how to reverse the + western medicine reversal agents more, but also made great progress, Chinese Herbal Medicine. C1l the existence of multidrug resistance reversal agents, a study reported in the tumor cells in vitro can reverse multidrug resistance, and non-toxic side effects. At present, there are advised to choose the role of Chinese medicine Fuzheng Tonifying (astragalus, cordyceps, ginseng, Psoraleae, coixenolide, bulb, etc.) to carry out clinical and experimental research on the appropriate focus on the effective compound, such as Liuweidihuangwan, Sijunzitang , Shenqi Pill, such as Bazhen Decoction.

Five Difficulties: How to transfer anti-lung cancer

Transfer is one of the basic characteristics of lung cancer, a direct impact on lung cancer + how to control the metastasis of lung cancer lung cancer treatment is difficult and is the current focus of the study one of the topics, how to make use of the transfer of anti-Chinese medicine in Chinese medicine treatment of lung cancer Difficulties and research priorities .
1, traditional Chinese medicine to control the transfer of the process of tumor cells using drugs to lower blood viscosity of blood, increasing blood flow, reducing the tumor cells and vessel wall contact and adhesion, it is possible to block part of the invasion process of tumor cells, reduce the incidence of tumor metastasis. Such as the Chinese medicine contains Ligustrazine Chuanxiong is huoxuehuayu active ingredient, inhibits platelet aggregation, animal experiments have anti-tumor metastasis. It should however be noted that not all Chinese medicine huoxuehuayu have anti-tumor metastasis, such as animal testing found that Chinese medicine Danshen huoxuehuayu, Chishao, safflower, Chinese angelica and promote tumor metastasis role there should be attention. In addition, traditional Chinese medicine compound huoxuehuayu complicated, different varieties of a direct impact on the experimental results, the study should focus on the single drug, there are active monomer of research.
2, inhibit tumor angiogenesis tumor angiogenesis is the proliferation of tumor proliferation and metastasis of an important condition for the -. Interfere with tumor angiogenesis, which can effectively control the proliferation and metastasis of tumors, some traditional Chinese medicine (ginseng, astragalus, cordyceps, dangshen, Ciwujia, medlar, Icariin. Kiwifruit) in this respect have a certain role, to be studied in depth.

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