Treatment of pleural effusion of lung cancer drug

Pleural effusion caused by lung cancer chemotherapy in the diagnosis of lung cancer when combined 1 percent of patients have a pleural effusion, has been no surgical indications. At this point, only to receive chemotherapy temporary effect. Commonly used drugs are as follows:

1, nitrogen mustard

Asepsis will be in the chest cavity effusion pumping as much as possible to do (also placed small ducts), according to 0.4mg/kg, diluted with saline 200m1, one into the chest, once the largest amount of not more than 20mg. Immediately after injection to allow patients to change the direction of position, continuing for about 15 minutes to ensure even distribution of all liquid surface of the chest cavity. Once a week. Effective rate was 55% ~ 87%, a week before and after the drug should pay attention to the situation of bone marrow function and whole body.

2. Ah Ping

Its response rate of about 64% ~ 88%, the drug will enable the emergence of inflammatory pleural adhesion, gap disappeared. The beginning of the available 50 ~ 100mg dissolved in saline injection in lomi chest, if the patient's response is not heavy, every 2 ~ 5, the further injection of 100 ~ 200mg, until the liquid until reduced. Can also be used 600 ~ 800mg single injection. The main reaction to fever, local pain, there are some low blood pressure patients.

3. Tetracyclines

Tetracycline as a hardening agent for cancer treatment of pleural effusion. Are generally placed in a sealed chest catheter to the tetracycline 500mg dissolved in 30ml normal saline into the thoracic cavity, and then injected saline 10m1 washing pipe, duct clamp 6 hours and at the same time continue to transform the body, and then suction drainage tube then about 24 hours to determine the non-liquid and then pull out the drainage tube. It is reported that patients on other drugs (nitrogen mustard, etc.) is invalid, the method succeeded in controlling the growth of liquid 3 ~ 19 months. Satoshi Kitamura also reported the use of doxycycline 500mg, 2 weeks Intrapleural injection 2 or 3 times, the liquid can completely disappear.

4. Other

Self-ADM of adenocarcinoma-induced pleural effusion is better, the chest cavity of a 6 ~ 12mg. In addition, canola can also be used Xiaoliu 30 ~ 40mg / meeting, 5 - fluorouracil 750 ~ 1000mg / times. There are colloidal gold (198Au) colloidal phosphate (32P) and the polio vaccine, Ⅱ, Ⅲ type vaccinia vaccine.